SCHEMBL25967424

SCHEMBL25967424

Cc1cc(F)c(N2CCC(COc3cccc4c3CSCC(=O)N4)CC2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 0.40
HTR1D P28221 3/20 0.37
MGLL Q99685 4/20 0.37
C5AR1 P21730 1/20 0.36
HTR1A P08908 2/20 0.35
HTR1B P28222 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20613076 0.89 SLC6A9 (0.39) HTR1DMGLL
SCHEMBL25967371 0.88 FFAR4 (0.43) FFAR4HTR1DMGLLC5AR1HTR1A
SCHEMBL20613099 0.79 FFAR4 (0.42) FFAR4MGLL
SCHEMBL25968580 0.78 FFAR4 (0.42) FFAR4MGLL
SCHEMBL20612865 0.77 FFAR4 (0.44) FFAR4C5AR1
SCHEMBL25967656 0.77 SLC6A9 (0.38) HTR1DC5AR1
SCHEMBL20613065 0.77 BRD4 (0.46) FFAR4C5AR1HTR1A
SCHEMBL20612924 0.76 PARP1 (0.46) FFAR4
SCHEMBL25970060 0.75 FFAR4 (0.40) FFAR4MGLL
SCHEMBL25968327 0.75 SLC6A9 (0.41) HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed