Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 13/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20612865 | 0.86 | FFAR4 (0.44) | FFAR4BRD4MRGPRX4 | |
| SCHEMBL20613065 | 0.85 | BRD4 (0.46) | FFAR4BRD4MRGPRX4 | |
| SCHEMBL25964887 | 0.78 | FFAR4 (0.41) | FFAR4 | |
| SCHEMBL25967371 | 0.77 | FFAR4 (0.43) | FFAR4 | |
| SCHEMBL25967424 | 0.76 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL25970060 | 0.74 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL20613099 | 0.73 | FFAR4 (0.42) | FFAR4 | |
| SCHEMBL25968580 | 0.73 | FFAR4 (0.42) | FFAR4 | |
| SCHEMBL25967188 | 0.72 | FFAR4 (0.41) | FFAR4 | |
| SCHEMBL25966865 | 0.71 | ADRB3 (0.46) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-A1 | PIPERIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2019-01-02 | — | — | EP | disclosed |