SCHEMBL25968580

SCHEMBL25968580

Cc1cc(F)c(N2CCC(COc3ccc(C)c4c3CC(=O)N4)CC2)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.42
MGLL Q99685 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20613099 0.93 FFAR4 (0.42) FFAR4MGLL
SCHEMBL20612908 0.83 MGLL (0.41) FFAR4MGLL
SCHEMBL25970060 0.79 FFAR4 (0.40) FFAR4MGLL
SCHEMBL25967424 0.78 FFAR4 (0.40) FFAR4MGLL
SCHEMBL20612937 0.78 FFAR4 (0.42) FFAR4
SCHEMBL25967371 0.77 FFAR4 (0.43) FFAR4MGLL
SCHEMBL25969105 0.76 MGLL (0.44) FFAR4MGLL
SCHEMBL20613065 0.75 BRD4 (0.46) FFAR4
SCHEMBL25964887 0.74 FFAR4 (0.41) FFAR4
SCHEMBL20612865 0.73 FFAR4 (0.44) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed