Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.33 |
| ▸ | DRD2 | P14416 | 7/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 4/20 | 0.31 |
| ▸ | HTR1D | P28221 | 4/20 | 0.31 |
| ▸ | HTR1B | P28222 | 4/20 | 0.31 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20597459 | 0.84 | TRPV4 (0.35) | DRD3DRD2DRD4HTR1AHTR1D | |
| SCHEMBL25968118 | 0.78 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL25969105 | 0.74 | MGLL (0.44) | DRD3DRD2HTR1AHTR1DHTR1B | |
| SCHEMBL25970553 | 0.74 | HSP90AA1 (0.33) | HTR1AHTR1DHTR1BHSP90AA1HSP90AB1 | |
| SCHEMBL20597104 | 0.71 | MGLL (0.33) | DRD3DRD2HTR1AHTR1DHTR1B | |
| SCHEMBL20597385 | 0.71 | TRPV4 (0.37) | — | |
| SCHEMBL17544184 | 0.71 | TRPV4 (0.33) | — | |
| SCHEMBL20597030 | 0.70 | TRPV4 (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL17542742 | 0.70 | TRPV4 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL17542937 | 0.70 | TRPV4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |