Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | HTR1D | P28221 | 6/20 | 0.39 |
| ▸ | HTR1B | P28222 | 6/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25969706 | 0.89 | MGLL (0.43) | MGLLHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL25969717 | 0.84 | MGLL (0.44) | MGLLHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL20612928 | 0.82 | MGLL (0.43) | MGLLHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL20612908 | 0.77 | MGLL (0.41) | MGLLFFAR4 | |
| SCHEMBL20613099 | 0.77 | FFAR4 (0.42) | MGLLFFAR4 | |
| SCHEMBL20597459 | 0.76 | TRPV4 (0.35) | MGLLHTR1AHTR1DHTR1BHTR7 | |
| SCHEMBL25968580 | 0.76 | FFAR4 (0.42) | MGLLFFAR4 | |
| SCHEMBL25967371 | 0.75 | FFAR4 (0.43) | MGLLHTR1AHTR1DHTR1BFFAR4 | |
| SCHEMBL25968161 | 0.74 | DRD3 (0.33) | HTR1AHTR1DHTR1BHTR7DRD3 | |
| SCHEMBL25968868 | 0.74 | FFAR4 (0.41) | MGLLFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |