Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25345792 | 0.92 | CASP1 (0.37) | CASP1PIN1BACE1FABP5FABP7 | |
| SCHEMBL25968400 | 0.89 | CASP1 (0.40) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968518 | 0.89 | CASP1 (0.39) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968407 | 0.88 | CASP1 (0.37) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968410 | 0.85 | CASP1 (0.36) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968601 | 0.85 | CASP1 (0.37) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968525 | 0.85 | CASP1 (0.37) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25344766 | 0.85 | CASP1 (0.37) | CASP1BACE1FABP5FABP7MDM2 | |
| SCHEMBL25968505 | 0.84 | CASP1 (0.37) | CASP1BACE1FABP5FABP7EPHX2 | |
| SCHEMBL25968519 | 0.84 | CASP1 (0.37) | CASP1BACE1FABP5FABP7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154724-A2 | PROCESSES AND COMPOUNDS FOR PREPARING SPIROLIGOMERS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-08-17 | — | — | WO | disclosed |