SCHEMBL25969176

SCHEMBL25969176

Cc1cc(C(C)(C)c2ccc(O)c(N3C(=O)c4ccc(C#Cc5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c2)ccc1O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.43
ESR2 Q92731 5/20 0.39
TYMS P04818 1/20 0.35
APP P05067 2/20 0.33
ANPEP P15144 1/20 0.33
DPP4 P27487 1/20 0.33
CA9 Q16790 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13595156 0.85 ESR1 (0.43) ESR1ESR2TYMSAPPALDH1A1
SCHEMBL9891724 0.84 ESR1 (0.43) ESR1ESR2TYMSAPPANPEP
SCHEMBL25969160 0.83 ESR1 (0.42) ESR1ESR2TYMSAPPALDH1A1
SCHEMBL23373912 0.82 ESR1 (0.38) ESR1ESR2TYMSANPEPDPP4
SCHEMBL822316 0.80 ESR1 (0.40) ESR1ESR2TYMSAPPANPEP
SCHEMBL2622758 0.79 ESR1 (0.41) ESR1ESR2TYMSAPPANPEP
SCHEMBL13966982 0.77 ESR1 (0.38) ESR1ESR2TYMSAPPANPEP
SCHEMBL21933189 0.76 PKM (0.38) ESR1ESR2TYMSALDH1A1KDM4E
SCHEMBL13966981 0.75 BRD4 (0.38) ESR1ESR2TYMSAPPALDH1A1
SCHEMBL13292495 0.74 BRD4 (0.38) ESR1ESR2TYMSAPPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230260787-A1 COMPOSITION FOR FORMING PROTECTIVE FILM AGAINST ALKALINE AQUEOUS HYDROGEN PEROXIDE, SUBSTRATE FOR PRODUCING SEMICONDUCTOR APPARATUS, METHOD FOR FORMING PROTECTIVE FILM, AND METHOD FOR FORMING PATTERN SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-17 US disclosed