Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596964 | 0.90 | CYP2D6 (0.38) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL17634470 | 0.81 | APP (0.35) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL14726006 | 0.81 | HRH3 (0.32) | CYP2D6CYP3A4HIF1A | |
| SCHEMBL14463277 | 0.81 | ALDH1A1 (0.54) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL13169006 | 0.81 | APP (0.37) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL2577142 | 0.79 | ALDH1A1 (0.61) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL28344188 | 0.78 | ALDH1A1 (0.64) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL24419882 | 0.77 | CYP1A2 (0.45) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL29356128 | 0.77 | CYP1A2 (0.40) | CYP2D6CYP1A2CYP2C19ALDH1A1APP | |
| SCHEMBL13224414 | 0.77 | CYP1A2 (0.40) | CYP2D6CYP1A2CYP2C19ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593497-B1 | SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS | DOW SILICONES CORP (US) | 2018-06-20 | — | — | EP | disclosed |
| US-9006372-B2 | Silicone resins and their use in polymer compositions | DOW CORNING (SHANGHAI) CO LTD (CN) | 2015-04-14 | — | — | US | disclosed |
| US-20140316045-A1 | Silicone Resins | DOW CORNING CORPORATION (US) | 2014-10-23 | — | — | US | disclosed |
| US-20140303299-A1 | Silicone Resins And Their Use in Polymers | DOW CORNING CORPORATION | 2014-10-09 | — | — | US | disclosed |
| EP-2780399-A2 | SILICONE RESINS COMPRISING METALLOSILOXANE | Dow Corning Corporation (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-2780398-A1 | SILICONE RESINS AND THEIR USE IN POLYMERS | Dow Corning Corporation (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-2780394-A1 | SILICONE RESINS | Dow Corning Corporation (US) | 2014-09-24 | — | — | EP | disclosed |
| US-20140249257-A1 | Silicone Resins Comprising Metallosiloxane | DOW CORNING CORPORATION (US) | 2014-09-04 | — | — | US | disclosed |
| WO-2013095812-A1 | SILICONE RESINS AND THEIR USE IN POLYMERS | DOW CORNING CORPORATION (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013072371-A1 | SILICONE RESINS | DOW CORNING CORPORATION (US) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072370-A2 | SILICONE RESINS COMPRISING METALLOSILOXANE | DOW CORNING CORPORATION (US) | 2013-05-23 | — | — | WO | disclosed |
| EP-2593497-A1 | SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS | Dow Corning Corporation (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-2593496-A1 | POLYMER COMPOSITIONS CONTAINING ALKOXYSILANES | Dow Corning Corporation (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-2571937-A2 | POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES | Dow Corning Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130065992-A1 | Polymer Compositions Containing Oxazine-Based Alkoxysilanes | DOW CORNING CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065993-A1 | Polymer Compositions Containing Alkoxysilanes | DOW CORNING CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130066009-A1 | Silicone Resins And Their Use In Polymer Compositions | DOW CORNING CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2011143931-A1 | SILICONE RESINS AND THEIR USE IN POLYMER COMPOSITIONS | DOW CORNING CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011143930-A1 | POLYMER COMPOSITIONS CONTAINING ALKOXYSILANES | DOW CORNING CORPORATIOM (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144575-A2 | POLYMER COMPOSITIONS CONTAINING OXAZINE-BASED ALKOXYSILANES | DOW CORNING CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |