Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480890 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BPLAUANPEPGRM7 | |
| SCHEMBL19688497 | 0.78 | PLAU (0.47) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL10557222 | 0.77 | PLAU (0.50) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL3611898 | 0.75 | PLAU (0.46) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL15882481 | 0.74 | TRPM8 (0.44) | CA1CA2 | |
| SCHEMBL17335654 | 0.74 | TRPM8 (0.44) | CA1CA2 | |
| SCHEMBL16594081 | 0.74 | PLAU (0.52) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL19671009 | 0.74 | PLAU (0.47) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL26491641 | 0.74 | PLAU (0.47) | MTNR1AMTNR1BPLAUANPEPCA1 | |
| SCHEMBL9568005 | 0.74 | TRPM8 (0.39) | MTNR1AMTNR1BPLAUANPEPGRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146610-A2 | AN ENANTIOSELECTIVE SYNTHESIS OF CHIRAL AMINES FOR THE PRODUCTION OF ROTIGOTINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-11-24 | — | — | WO | claimed |