Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 2/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048118 | 0.82 | PTGIR (0.36) | TRPM8MEN1KMT2A | |
| SCHEMBL9048122 | 0.80 | PTGIR (0.58) | — | |
| SCHEMBL9048119 | 0.80 | PTGIR (0.42) | MTNR1BMTNR1A | |
| SCHEMBL9567970 | 0.76 | TDP1 (0.39) | PLAUMTNR1BMTNR1AANPEPTDP1 | |
| SCHEMBL9567950 | 0.75 | TRPM8 (0.48) | TRPM8MTNR1B | |
| SCHEMBL2597095 | 0.74 | MTNR1A (0.46) | PLAUMTNR1BMTNR1AANPEPGRM7 | |
| SCHEMBL3611898 | 0.72 | PLAU (0.46) | PLAUMTNR1BMTNR1AANPEP | |
| SCHEMBL9427232 | 0.71 | PTGIR (0.36) | TRPM8MEN1KMT2ATDP1 | |
| SCHEMBL8291565 | 0.70 | DPP8 (0.39) | TRPM8MTNR1BMTNR1AGRM7 | |
| SCHEMBL11472821 | 0.70 | MTNR1A (0.45) | PLAUMTNR1BMTNR1AANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |