Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599232 | 0.89 | LIPG (0.35) | HAVCR2 | |
| SCHEMBL1663156 | 0.85 | HAVCR2 (0.35) | HAVCR2PDPK1 | |
| SCHEMBL14719753 | 0.85 | LIPG (0.34) | HAVCR2 | |
| SCHEMBL1661264 | 0.78 | HAVCR2 (0.34) | HAVCR2 | |
| SCHEMBL2597135 | 0.77 | HAVCR2 (0.32) | HAVCR2 | |
| SCHEMBL4628060 | 0.76 | HAVCR2 (0.33) | HAVCR2 | |
| Benzoylenurea SCHEMBL15948987 | 0.76 | KDM4E (0.34) | HAVCR2PDPK1 | |
| SCHEMBL14719786 | 0.76 | CD274 (0.36) | — | |
| SCHEMBL1661316 | 0.75 | USP1 (0.32) | HAVCR2 | |
| SCHEMBL1660973 | 0.75 | CCNK (0.37) | HAVCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571865-A1 | 2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL-SULFONAMIDE DERIVATIVES | Novartis AG (CH) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144666-A1 | 2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL-SULFONAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-11-24 | — | — | WO | disclosed |