Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16438490 | 0.86 | RIPK1 (0.42) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL12640147 | 0.84 | CES2 (0.41) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL1598076 | 0.82 | PDE7A (0.41) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL1300316 | 0.82 | CNR2 (0.42) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL12824157 | 0.82 | SIGMAR1 (0.46) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL16435721 | 0.80 | RIPK1 (0.41) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL20869273 | 0.78 | TDP1 (0.38) | RIPK1KDM4ECES2CES1CXCR3 | |
| SCHEMBL483677 | 0.78 | BCHE (0.50) | RIPK1KDM4ECES2CES1DPP4 | |
| SCHEMBL4436300 | 0.78 | CES2 (0.42) | RIPK1KDM4ECES2CES1USP2 | |
| SCHEMBL11774397 | 0.77 | BCHE (0.50) | KDM4EALDH1A1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227310-A1 | CAMPTOTHECIN DERIVATIVE AND LIGAND-DRUG CONJUGATE THEREOF | Sichuan Baili Pharmaceutical Co. Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |