Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25337204 | 0.86 | KDM4E (0.40) | CCR5KDM4EPARP1PDE10A | |
| SCHEMBL25338184 | 0.86 | KDM4E (0.40) | CCR5KDM4EPARP1PDE10A | |
| SCHEMBL25340117 | 0.86 | KDM4E (0.40) | CCR5KDM4EPARP1PDE10A | |
| SCHEMBL8802407 | 0.84 | THRB (0.48) | CCR5KDM4EPARP1ALDH1A1PDE10A | |
| SCHEMBL25973876 | 0.84 | CCR5 (0.40) | CCR5TERTVCPPARP1CHRM2 | |
| SCHEMBL25338364 | 0.84 | CCR5 (0.40) | CCR5TERTVCPPARP1CHRM2 | |
| SCHEMBL26766523 | 0.84 | CCR5 (0.41) | CCR5TERTVCPPARP1CHRM2 | |
| SCHEMBL25340159 | 0.84 | CCR5 (0.41) | CCR5TERTVCPPARP1CHRM2 | |
| SCHEMBL25339692 | 0.82 | KDM4E (0.50) | CCR5KDM4EPARP1PDE10A | |
| SCHEMBL31701791 | 0.81 | DRD2 (0.44) | CNR1CCR5VCPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |