Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973903 | 0.87 | NPC1 (0.39) | TRPV1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL25973973 | 0.86 | THRB (0.41) | TRPV1PDE10ARAB9A | |
| SCHEMBL25340813 | 0.85 | KCNH2 (0.38) | TRPV1ALOX5APFEN1PDE10ARAB9A | |
| SCHEMBL30519411 | 0.85 | KCNH2 (0.38) | TRPV1ALOX5APFEN1PDE10ARAB9A | |
| SCHEMBL25375442 | 0.85 | FEN1 (0.38) | ALOX5APFEN1RAB9A | |
| SCHEMBL25973899 | 0.82 | FEN1 (0.51) | ALOX5APFEN1PDE10A | |
| SCHEMBL25974745 | 0.82 | KIF11 (0.51) | PDE10ANPC1RAB9A | |
| SCHEMBL25341793 | 0.80 | TRPV1 (0.47) | TRPV1RAB9A | |
| SCHEMBL30519393 | 0.80 | TRPV1 (0.47) | TRPV1RAB9A | |
| SCHEMBL25975488 | 0.80 | PDE10A (0.35) | TRPV1PDE10ANPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |