Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.46 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341074 | 0.85 | KIF11 (0.51) | KIF11MAPK1PDE10AALDH1A1NPC1 | |
| SCHEMBL25973972 | 0.82 | TRPV1 (0.39) | PDE10ANPC1RAB9A | |
| SCHEMBL25973903 | 0.82 | NPC1 (0.39) | ALDH1A1NPC1RAB9AMAPTATM | |
| SCHEMBL25973973 | 0.81 | THRB (0.41) | PDE10AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL25340058 | 0.81 | KIF11 (0.48) | KIF11PDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25341777 | 0.80 | TRPV1 (0.38) | KIF11PDE10AALDH1A1MAPTATM | |
| SCHEMBL25375442 | 0.80 | FEN1 (0.38) | RAB9ASMN1; SMN2 | |
| SCHEMBL30519281 | 0.80 | TRPV1 (0.38) | KIF11PDE10AALDH1A1MAPTATM | |
| SCHEMBL25974746 | 0.79 | PDE10A (0.37) | PDE10A | |
| SCHEMBL25378460 | 0.79 | GRM4 (0.45) | PDE10AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |