SCHEMBL25974305

SCHEMBL25974305

CC(C)(C)OCCc1cn(C(C)(C)C)nn1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.32
▸ CYP4A11 Q02928 1/20 0.32
▸ GABRA2 P47869 1/20 0.30
▸ GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25974304 0.90 CYP4F2 (0.35) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL25751753 0.82 RXRA (0.35) —
SCHEMBL14900340 0.80 GABRA2 (0.34) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL14212090 0.80 GABRA2 (0.38) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL14900333 0.79 CYP4F2 (0.31) CYP4F2CYP4A11
SCHEMBL15222209 0.78 GABRA2 (0.45) GABRA2GABRB2
SCHEMBL16216284 0.78 GABRA2 (0.33) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL25588830 0.77 DDX3X (0.41) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL14212094 0.77 NOTUM (0.41) CYP4F2CYP4A11GABRA2GABRB2
SCHEMBL25734935 0.77 GABRA2 (0.32) GABRA2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A CYP4F2 3314/4885CYP4A11 4275/4885GABRA2 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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