Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638978 | 0.82 | L3MBTL1 (0.52) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL13753946 | 0.80 | LTA4H (0.46) | L3MBTL1ALDH1A1SLC6A4TSHRKMT2A | |
| SCHEMBL5375024 | 0.77 | AR (0.54) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL25974635 | 0.77 | SLC6A4 (0.37) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL9589622 | 0.76 | AR (0.52) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL14677727 | 0.75 | LTA4H (0.52) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL9589613 | 0.75 | AR (0.51) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL25340059 | 0.74 | L3MBTL1 (0.41) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL21858140 | 0.74 | SLC6A4 (0.47) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 | |
| SCHEMBL3748483 | 0.74 | L3MBTL1 (0.41) | MAPK14L3MBTL1RAB9ACACNA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |