Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236875 | 0.79 | CA1 (0.36) | SLC6A4AHRL3MBTL1RAB9AMEN1 | |
| SCHEMBL25974598 | 0.77 | MAPK14 (0.40) | SLC6A4AHRCACNA1BL3MBTL1RAB9A | |
| SCHEMBL21765157 | 0.75 | MEN1 (0.39) | L3MBTL1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18428342 | 0.74 | PTGS1 (0.35) | AHRKDM4ECA1CA2CA9 | |
| SCHEMBL28638978 | 0.73 | L3MBTL1 (0.52) | SLC6A4CACNA1BL3MBTL1RAB9AKMT2A | |
| SCHEMBL23288678 | 0.71 | HTR2A (0.35) | KMT2AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL29317108 | 0.71 | CES2 (0.39) | MEN1KMT2A | |
| SCHEMBL23312577 | 0.70 | — | — | |
| SCHEMBL22791773 | 0.69 | TSHR (0.36) | L3MBTL1RAB9AMAPTLMNAKDM4E | |
| SCHEMBL24074578 | 0.69 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |