Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22005073 | 0.79 | DRD2 (0.50) | OPRM1DRD2 | |
| SCHEMBL23381592 | 0.79 | ALDH1A1 (0.43) | OPRM1DRD2DRD3 | |
| SCHEMBL15166922 | 0.79 | OPRM1 (0.42) | OPRM1CCR1DRD2DRD4DRD3 | |
| SCHEMBL9966015 | 0.78 | OPRM1 (0.48) | OPRM1DRD4 | |
| SCHEMBL30913193 | 0.77 | SLC6A4 (0.38) | OPRM1DRD4 | |
| SCHEMBL18587400 | 0.77 | SMN1; SMN2 (0.36) | OPRM1DRD2DRD4DRD3 | |
| SCHEMBL30913192 | 0.77 | SLC6A4 (0.38) | OPRM1DRD4 | |
| SCHEMBL18588194 | 0.75 | OPRM1 (0.42) | OPRM1CNR1 | |
| SCHEMBL18296429 | 0.75 | DRD2 (0.43) | OPRM1CCR1DRD2DRD4DRD3 | |
| SCHEMBL14562542 | 0.75 | DRD2 (0.43) | OPRM1CCR1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |