Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172147 | 0.83 | ALDH1A1 (0.48) | HPGDTSHRTDP1POLBALDH1A1 | |
| SCHEMBL945226 | 0.83 | ALDH1A1 (0.48) | HPGDTSHRTDP1POLBALDH1A1 | |
| SCHEMBL27978123 | 0.83 | PSMB11 (0.46) | HPGDTSHRMAPK1TDP1POLB | |
| SCHEMBL9318651 | 0.81 | KDM4E (0.54) | PPARGPPARDPPARAHPGDMAPT | |
| SCHEMBL25794495 | 0.81 | BRD4 (0.40) | — | |
| SCHEMBL8765637 | 0.81 | HPGD (0.61) | HPGDGAAMAPTTSHRNPC1 | |
| SCHEMBL18636751 | 0.81 | TGM2 (0.44) | LMNAHPGDGAAMAPTMAPK1 | |
| SCHEMBL25781046 | 0.80 | EPHX2 (0.45) | LMNAHPGDNPC1POLBALDH1A1 | |
| SCHEMBL9318911 | 0.79 | HPGD (0.51) | PPARGPPARDPPARAHPGDGAA | |
| SCHEMBL5082960 | 0.79 | NPC1 (0.55) | LMNAHPGDGAAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |