Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29157949 | 0.84 | EGFR (0.49) | TGM2MAPT | |
| SCHEMBL5082960 | 0.83 | NPC1 (0.55) | TGM2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28973935 | 0.82 | PKM (0.55) | TGM2KMT2AHTTHPGDPKM | |
| SCHEMBL18630147 | 0.82 | TGM2 (0.49) | TGM2MEN1KMT2AUSP2MAPK1 | |
| SCHEMBL28987060 | 0.81 | TGM2 (0.49) | TGM2KMT2AMAPK1GAA | |
| SCHEMBL8983177 | 0.81 | MEN1 (0.49) | TGM2NPSR1MEN1KMT2AUSP2 | |
| SCHEMBL27736017 | 0.81 | MCL1 (0.43) | TGM2MEN1KMT2AMAPK1NPC1 | |
| SCHEMBL27965323 | 0.81 | CA1 (0.53) | TGM2GAALMNA | |
| SCHEMBL25976165 | 0.81 | MAPK8 (0.44) | KMT2AMAPK1NPC1GAAMAPT | |
| SCHEMBL2264130 | 0.80 | TGM2 (0.50) | TGM2KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141567-B1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GMBH (DE) | 2019-08-28 | — | — | EP | disclosed |
| EP-3141567-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GmbH (DE) | 2017-03-15 | — | — | EP | disclosed |