Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898535 | 0.91 | TSHR (0.67) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL7422565 | 0.81 | TSHR (0.51) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL14613161 | 0.80 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL1492404 | 0.80 | TSHR (0.65) | TSHRL3MBTL1ALDH1A1HSD17B10CDC25B | |
| SCHEMBL2644268 | 0.80 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL13032652 | 0.79 | TSHR (0.67) | TSHRL3MBTL1ALDH1A1HSD17B10CDC25B | |
| SCHEMBL1492385 | 0.79 | TSHR (0.67) | TSHRL3MBTL1ALDH1A1HSD17B10CDC25B | |
| SCHEMBL1567252 | 0.79 | TSHR (0.52) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL28600642 | 0.79 | TSHR (0.52) | TSHRL3MBTL1ALDH1A1HSD17B10PKM | |
| SCHEMBL6959476 | 0.79 | TSHR (0.67) | TSHRL3MBTL1ALDH1A1HSD17B10CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571860-A1 | 2-PHENYL BENZOYLAMIDES | Pfizer Inc (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |