Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898535 | 0.86 | TSHR (0.67) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL1567252 | 0.86 | TSHR (0.52) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL68340 | 0.85 | PKM (0.60) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL14613161 | 0.85 | TSHR (0.50) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL10209861 | 0.82 | LMNA (0.47) | TSHRCYP4F2CYP4A11HSD17B10ALDH1A1 | |
| SCHEMBL7422565 | 0.82 | TSHR (0.51) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL9032748 | 0.82 | PKM (0.48) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL6878047 | 0.82 | PKM (0.57) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL31424953 | 0.82 | PKM (0.57) | TSHRPKMCYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL31424955 | 0.82 | PKM (0.57) | TSHRPKMCYP4F2CYP4A11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156820-B | Mercaptoamide boronic acid derivatives and application thereof as MBL (sodium Bromide) and/or SBL (SBL) inhibitor | 四川大学 | 2021-06-25 | — | — | CN | disclosed |