Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340405 | 0.81 | PTGS2 (0.48) | TRPV1 | |
| SCHEMBL25977697 | 0.79 | SLC6A4 (0.45) | TRPV1SLC6A4HTR2AKCNH2SLC6A2 | |
| SCHEMBL25377773 | 0.78 | TSHR (0.47) | TRPV1AHR | |
| SCHEMBL2882139 | 0.73 | AHR (0.50) | AHRP2RY1ALDH1A1MAPTATM | |
| SCHEMBL25378083 | 0.71 | SLC6A4 (0.43) | TRPV1SLC6A4KCNH2AHRMAPT | |
| SCHEMBL25338761 | 0.71 | KMT2A (0.43) | TRPV1SLC6A4HTR2AKCNH2AHR | |
| SCHEMBL1328756 | 0.71 | KCNH2 (0.45) | TRPV1KCNH2MAPK14AHRMAPT | |
| SCHEMBL25427626 | 0.70 | HSD17B10 (0.51) | TRPV1MAPK14ALDH1A1 | |
| SCHEMBL695441 | 0.69 | ALDH1A1 (0.43) | SLC6A4SLC6A2SLC6A3ALDH1A1ATM | |
| SCHEMBL2861648 | 0.69 | TRPV1 (0.68) | TRPV1TOP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |