Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444066 | 0.84 | PTGS2 (0.58) | SLC6A4HTR2AKCNH2NCOA1NCOA3 | |
| SCHEMBL28672016 | 0.84 | NCOA1 (0.62) | NCOA1NCOA3PTGS2ARBACE1 | |
| SCHEMBL25429460 | 0.81 | KIF11 (0.53) | NCOA1NCOA3PTGS2ARBACE1 | |
| SCHEMBL25973310 | 0.80 | PTGS2 (0.45) | NCOA1NCOA3PTGS2ARBACE1 | |
| SCHEMBL25977136 | 0.79 | TRPV1 (0.40) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL25430418 | 0.78 | PTGS2 (0.72) | PTGS2CACNA1B | |
| SCHEMBL3992772 | 0.78 | AR (0.48) | SLC6A4HTR2AKCNH2NCOA1NCOA3 | |
| SCHEMBL25977864 | 0.77 | NCOA1 (0.41) | SLC6A4NCOA1NCOA3PTGS2AR | |
| SCHEMBL25343498 | 0.77 | CYP2C8 (0.53) | NCOA1NCOA3PTGS2BACE1FFAR4 | |
| SCHEMBL25429840 | 0.77 | PTGS2 (0.51) | NCOA1NCOA3PTGS2ARBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |