Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597994 | 1.00 | ATM (0.41) | ATMOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL12185862 | 0.86 | CTRB1 (0.42) | ALDH1A1MDM2 | |
| SCHEMBL12185427 | 0.85 | ALDH1A1 (0.40) | ATMOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL12185898 | 0.84 | ALDH1A1 (0.39) | ATMKCNH2ALDH1A1MAPTHPGD | |
| SCHEMBL2599307 | 0.81 | ALDH1A1 (0.42) | OPRM1ALDH1A1MAPTCA12CA9 | |
| SCHEMBL2599267 | 0.81 | ALDH1A1 (0.42) | OPRM1ALDH1A1MAPTCA12CA9 | |
| SCHEMBL2597754 | 0.81 | ALDH1A1 (0.42) | OPRM1ALDH1A1MAPTCA12CA9 | |
| SCHEMBL12185417 | 0.80 | OPRM1 (0.42) | ATMOPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL12185899 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13136409 | 0.71 | MDM2 (0.44) | ALDH1A1MAPTKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |