Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213435 | 0.82 | SLC6A2 (0.53) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL168005 | 0.82 | SLC6A2 (0.53) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3884171 | 0.77 | SIRT2 (0.43) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6131533 | 0.77 | TP53 (0.47) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6555382 | 0.74 | MAPT (0.52) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL162322 | 0.74 | MAPT (0.52) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8930563 | 0.73 | KDM4E (0.47) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4310308 | 0.73 | MAPT (0.46) | MAPTALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL2486332 | 0.72 | TAAR1 (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20581696 | 0.72 | MAPT (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399356-A1 | ANTIBODY DRUG CONJUGATES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-14 | — | — | US | disclosed |
| US-11725024-B2 | Antibody drug conjugates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399356-A1 | ANTIBODY DRUG CONJUGATES | STING1, CGAS, TBK1 | MAPT 3123/4885ALDH1A1 4494/4885KDM4E 2002/4885 |
| US-11725024-B2 | Antibody drug conjugates | STING1, CGAS, TBK1 | MAPT 3123/4885ALDH1A1 4494/4885KDM4E 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.