Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168005 | 0.79 | SLC6A2 (0.53) | MAPTMEN1SLC6A3KMT2AHSD17B10 | |
| SCHEMBL31213435 | 0.79 | SLC6A2 (0.53) | MAPTMEN1SLC6A3KMT2AHSD17B10 | |
| SCHEMBL6555382 | 0.78 | MAPT (0.52) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL162322 | 0.78 | MAPT (0.52) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL11795231 | 0.78 | HTR1A (0.53) | HTR1AMAPTLMNAHSD17B10ALDH1A1 | |
| SCHEMBL334956 | 0.77 | KMT2A (0.47) | TP53MAPTMEN1NR1I2LMNA | |
| SCHEMBL542238 | 0.77 | SCN1A (0.51) | TP53HTR1AMAPTMEN1NR1I2 | |
| SCHEMBL25978795 | 0.77 | MAPT (0.40) | TP53MAPTMEN1NR1I2LMNA | |
| SCHEMBL7214875 | 0.76 | HTR1A (0.47) | TP53HTR1AMAPTMEN1NR1I2 | |
| SCHEMBL20581696 | 0.76 | MAPT (0.50) | MAPTMEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550657-A1 | AMINE COMPOUNDS AND USE THEREOF | Kureha Chemical Industry Co., Ltd. (JP) | 2005-07-06 | — | — | EP | disclosed |