Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.41 |
| ▸ | QDPR | P09417 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663812 | 1.00 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL18640033 | 1.00 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL16553704 | 0.87 | QDPR (0.46) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL14864496 | 0.84 | PDE4B (0.39) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL20501161 | 0.84 | MRGPRX4 (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL20500519 | 0.84 | ALDH1A1 (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL25980344 | 0.84 | MRGPRX4 (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL20500607 | 0.84 | MRGPRX4 (0.41) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL22596194 | 0.83 | NR3C1 (0.42) | PDE4APDE4BPDE4CPDE4DQDPR | |
| SCHEMBL21876219 | 0.81 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113056271-B | Fanisole X receptor agonist and application thereof | 奥加诺沃公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-110637011-B | Fanisole X receptor agonist and application thereof | 奥加诺沃公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-110637015-B | Fanisole X receptor agonist and application thereof | 奥加诺沃公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-3596053-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-08-16 | — | — | EP | disclosed |