SCHEMBL25980398

SCHEMBL25980398

c1ccc(-c2ccc(N(c3ccccc3)c3cccc4c3oc3cc(-c5nc(-c6ccccc6)nc6c5sc5ccccc56)ccc34)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR2 Q92731 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PRKDC P78527 1/20 0.31
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25980397 0.96 ESR2 (0.31) POLBLMNAMAPTTSHRHTT
SCHEMBL24849044 0.91 ALDH1A1 (0.36) POLBLMNAMAPTTSHRHTT
SCHEMBL26779000 0.89 PRKDC (0.31) POLBLMNAMAPTTSHRHTT
SCHEMBL25978618 0.89 PRKDC (0.31) POLBLMNAMAPTTSHRHTT
SCHEMBL25979975 0.88 LIMK1 (0.32) PRKDCLIMK1
SCHEMBL25978640 0.87 LIMK1 (0.31) PRKDCLIMK1
SCHEMBL25978638 0.87 LIMK1 (0.31) PRKDCLIMK1
SCHEMBL25978596 0.86 PRKDC (0.31) PRKDCLIMK1
SCHEMBL25978616 0.86 PRKDC (0.31) PRKDCLIMK1
SCHEMBL26416508 0.86 PRKDC (0.34) ESR2PRKDCLIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-11-16 US disclosed
US-20230365538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-11-16 US disclosed
EP-4227301-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 POLB 2906/4885LMNA 3768/4885MAPT 1428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.