Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479638 | 0.84 | UCHL1 (0.42) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL30479646 | 0.84 | UCHL1 (0.44) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL25980444 | 0.84 | UCHL1 (0.42) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL3205346 | 0.84 | UCHL1 (0.44) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL25980452 | 0.83 | UCHL1 (0.41) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL30479623 | 0.83 | UCHL1 (0.41) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL25980402 | 0.83 | UCHL1 (0.41) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL30479612 | 0.83 | UCHL1 (0.41) | UCHL1KDM1ABCHEHDAC1HDAC6 | |
| SCHEMBL3203157 | 0.80 | TDP1 (0.40) | UCHL1KDM1AHDAC1HDAC6NR1H2 | |
| SCHEMBL13487003 | 0.78 | UCHL1 (0.40) | UCHL1KDM1AHDAC1HDAC6NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |