Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 9/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479646 | 1.00 | UCHL1 (0.44) | UCHL1RORCKDM1AHDAC1HDAC6 | |
| SCHEMBL7920801 | 0.88 | KDM4E (0.42) | RORCKDM1AHDAC1HDAC6 | |
| SCHEMBL13486998 | 0.84 | UCHL1 (0.40) | UCHL1KDM1AHDAC1HDAC6NR1H2 | |
| SCHEMBL13487004 | 0.84 | UCHL1 (0.40) | UCHL1KDM1AHDAC1HDAC6NR1H2 | |
| SCHEMBL13487003 | 0.84 | UCHL1 (0.40) | UCHL1KDM1AHDAC1HDAC6NR1H2 | |
| SCHEMBL25980404 | 0.84 | UCHL1 (0.43) | UCHL1RORCKDM1AHDAC1HDAC6 | |
| SCHEMBL6975852 | 0.82 | RORC (0.45) | RORCKDM1A | |
| SCHEMBL30479638 | 0.82 | UCHL1 (0.42) | UCHL1RORCKDM1AHDAC1HDAC6 | |
| SCHEMBL25980444 | 0.82 | UCHL1 (0.42) | UCHL1RORCKDM1AHDAC1HDAC6 | |
| SCHEMBL3216506 | 0.82 | SIRT1 (0.36) | UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | UCHL1 2156/4885RORC 1022/4885KDM1A 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.