Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479623 | 1.00 | UCHL1 (0.41) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL30479612 | 0.89 | UCHL1 (0.41) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL25980402 | 0.89 | UCHL1 (0.41) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL25980404 | 0.83 | UCHL1 (0.43) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL25344511 | 0.82 | SIRT2 (0.33) | USP30 | |
| SCHEMBL3205346 | 0.81 | UCHL1 (0.44) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL30479638 | 0.81 | UCHL1 (0.42) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL25980444 | 0.81 | UCHL1 (0.42) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL30479646 | 0.81 | UCHL1 (0.44) | UCHL1KDM1ANR1H2NR1H3HDAC1 | |
| SCHEMBL3203157 | 0.78 | TDP1 (0.40) | UCHL1KDM1ANR1H2NR1H3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148501-A1 | HETEROCYCLIC DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-08-10 | — | — | WO | disclosed |