Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211494 | 0.90 | HDAC6 (0.53) | HDAC6HDAC1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL25981737 | 0.89 | HDAC6 (0.46) | HDAC6HDAC1HDAC8HDAC5LTB4R2 | |
| SCHEMBL16211649 | 0.88 | SMN1; SMN2 (0.50) | HDAC6HDAC1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL25979367 | 0.86 | HDAC6 (0.64) | HDAC6HDAC1HDAC8ALDH1A1HDAC5 | |
| SCHEMBL25981731 | 0.83 | ALDH1A1 (0.42) | HDAC6HDAC1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL25980807 | 0.81 | L3MBTL1 (0.38) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL16211465 | 0.79 | HDAC8 (0.48) | HDAC6HDAC1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL16211432 | 0.78 | HDAC6 (0.52) | HDAC6HDAC1HDAC8HDAC5LTB4R2 | |
| SCHEMBL16211299 | 0.78 | HDAC6 (0.54) | HDAC6HDAC1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL25979308 | 0.78 | TSHR (0.41) | SMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | HDAC6 997/4885HDAC1 1635/4885HDAC8 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.