Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25980910 | 0.90 | HDAC1 (0.43) | RAB9ANPC1SMN1; SMN2MAPTEPHX2 | |
| SCHEMBL25980920 | 0.86 | L3MBTL1 (0.42) | RAB9ANPC1ALDH1A1HPGDMEN1 | |
| SCHEMBL22218749 | 0.83 | GAA (0.43) | RAB9ANPC1SMN1; SMN2MAPTEPHX2 | |
| SCHEMBL25981775 | 0.82 | HPGD (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL22218776 | 0.82 | ALDH1A1 (0.42) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL25980785 | 0.81 | HDAC1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL16211346 | 0.80 | STAT3 (0.46) | KDM4EALDH1A1USP2ESR1CYP2D6 | |
| SCHEMBL25980822 | 0.80 | HDAC1 (0.46) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL22217968 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2EPHX2KDM4EALDH1A1HPGD | |
| SCHEMBL25981781 | 0.78 | HDAC1 (0.49) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230248735-A1 | COMPOSITIONS FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASES (COPD) | NR1H2, CFTR, CYP11B2 | RAB9A 2535/4885NPC1 176/4885SMN1; SMN2 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.