SCHEMBL2598174

SCHEMBL2598174

CCCOC(C)OP(=O)(O)OC(C)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.32
SMPD1 P17405 3/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2522276 0.92 METAP1 (0.36) METAP1SMPD1FDPS
SCHEMBL18422355 0.87 LMNA (0.41) METAP1SMPD1FDPS
SCHEMBL2598057 0.85 LMNA (0.42) METAP1FDPS
SCHEMBL2524893 0.82 CA2 (0.33)
SCHEMBL2520483 0.81 LPAR3 (0.40) SMPD1FDPS
SCHEMBL2046370 0.80 SMPD1 (0.42) METAP1SMPD1FDPS
SCHEMBL20213335 0.80 PIK3CD (0.30)
SCHEMBL2521045 0.78 LPAR3 (0.50) SMPD1FDPS
SCHEMBL2523264 0.78 LPAR3 (0.50) SMPD1FDPS
SCHEMBL18423586 0.76 LMNA (0.38) SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571914-B1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX MITSUI CHEMICALS INC (JP) 2021-12-29 EP disclosed
US-10294198-B2 Method for producing xylylene diisocyanates in the gaseous phase COVESTRO DEUTSCHLAND AG (DE) 2019-05-21 US disclosed
US-10252988-B2 Composition for producing transparent polythiourethane bodies COVESTRO DEUTSCHLAND AG (DE) 2019-04-09 US disclosed
EP-3337839-A1 BATCH PROCESS FOR PREPARING MOLDED OPTICAL ARTICLES PPG Industries Ohio, Inc. (US) 2018-06-27 EP disclosed
US-20170210702-A1 METHOD FOR PRODUCING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2017-07-27 US disclosed
US-20170121449-A1 COMPOSITION FOR PRODUCING TRANSPARENT POLYTHIOURETHANE BODIES MITSUI CHEMICALS, INC. (JP) 2017-05-04 US disclosed
WO-2017035046-A1 BATCH PROCESS FOR PREPARING MOLDED OPTICAL ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2017-03-02 WO disclosed
US-20170052284-A1 Batch Process for Preparing Molded Optical Articles PPG INDUSTRIES OHIO, INC. 2017-02-23 US disclosed
US-9568644-B2 Polymerization catalyst for polythiourethanes, polymerizable liquid composition and process for the production of organic polythiourethane glass with a high refractive index MITSUI CHEMICALS, INC. (JP) 2017-02-14 US disclosed
US-20170029552-A1 COMPOSITION CONTAINING AROMATIC NITRILES FOR THE PRODUCTION OF TRANSPARENT POLYTHIOURETHANE BODIES COVESTRO DEUTSCHLAND AG (DE) 2017-02-02 US disclosed
US-20140323678-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX MITSUI CHEMICALS, INC. (JP) 2014-10-30 US disclosed
EP-2571914-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX Mitsui Chemicals, Inc. (JP) 2013-03-27 EP disclosed
US-20130066034-A1 POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX MITSUI CHEMICALS, INC. (JP) 2013-03-14 US disclosed
WO-2011144995-A1 A POLYMERIZATION CATALYST FOR POLYTHIOURETHANES, POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC POLYTHIOURETHANE GLASS WITH A HIGH REFRACTIVE INDEX ACOMON AG (CH) 2011-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10252988-B2 Composition for producing transparent polythiourethane bodies PHOSPHO1, PCTP, AGPAT5 METAP1 1876/4885SMPD1 178/4885FDPS 488/4885
US-10294198-B2 Method for producing xylylene diisocyanates in the gaseous phase DCXR, DAD1, PAG1 METAP1 2107/4885SMPD1 2495/4885FDPS 83/4885
US-20170210702-A1 METHOD FOR PRODUCING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE DCXR, DAD1, PAG1 METAP1 2107/4885SMPD1 2495/4885FDPS 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.