SCHEMBL25983003

SCHEMBL25983003

C[SH](C)c1cc(C(C)(C)C)cs1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19187341 0.71 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL50658 0.69 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL10153919 0.69 DAO (0.38) GABRA1GABRB2
SCHEMBL16806316 0.67 DAO (0.37) GABRA1GABRB2
SCHEMBL21720113 0.67 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL21737225 0.67 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL5057445 0.67 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL18540827 0.64 DAO (0.35) GABRA1GABRB2
SCHEMBL8130441 0.64 KIF11 (0.33) GABRA1GABRB2
SCHEMBL21720505 0.64 GABRA1 (0.31) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255950-A1 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same GEORGIA TECH RESEARCH CORPORATION 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255950-A1 3-(Hydroxy)-Pyridin-4(1H)-One Compounds and Methods of Making and Using the Same KDM1B, KDM3A, KDM1A GABRA1 2559/4885GABRB2 2795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.