SCHEMBL5057445

SCHEMBL5057445

[Li]c1cc(C(C)(C)C)cs1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50658 0.72 GABRA1 (0.35) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL10153919 0.72 DAO (0.38) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL19187341 0.70 GABRA1 (0.33) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL21720113 0.70 GABRA1 (0.33) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL21737225 0.70 GABRA1 (0.33) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL16806316 0.70 DAO (0.37) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL3154022 0.67 GABRA1 (0.52) GABRA1GABRB2POLBALDH1A1HPGD
SCHEMBL8130441 0.67 KIF11 (0.33) GABRA1GABRB2
SCHEMBL25983003 0.67 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL21720505 0.67 GABRA1 (0.31) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US disclosed
WO-2006093467-A1 CONJUGATED ORGANIC MOLECULES FOR MOLECULAR ELECTRONIC DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2006-09-08 WO disclosed