Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212293 | 1.00 | CSNK2A2 (0.52) | CSNK2A2CSNK2BLMNAHTTMAPK1 | |
| SCHEMBL25983146 | 0.89 | NPC1 (0.47) | LMNARAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31212371 | 0.89 | NPC1 (0.47) | LMNARAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL31212242 | 0.89 | SMN1; SMN2 (0.43) | CSNK2A2CSNK2BLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL25983148 | 0.89 | SMN1; SMN2 (0.43) | CSNK2A2CSNK2BLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL25983252 | 0.84 | NAMPT (0.41) | CSNK2A2CSNK2BLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL25981084 | 0.84 | SMN1; SMN2 (0.67) | CSNK2A2CSNK2BLMNAHTTRAB9A | |
| SCHEMBL31212156 | 0.83 | SMN1; SMN2 (0.43) | CSNK2A2CSNK2BLMNAHTTRAB9A | |
| SCHEMBL31529357 | 0.83 | LMNA (0.65) | LMNAHTTMAPK1RAB9AKDM4E | |
| SCHEMBL31212343 | 0.80 | SMN1; SMN2 (0.40) | LMNAHTTRAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
| WO-2023150663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | RETUNE PHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | IGF1R, IGFBP1, IGFBP2 | CSNK2A2 548/4885CSNK2B 510/4885LMNA 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.