Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598449 | 0.81 | L3MBTL1 (0.40) | L3MBTL1P2RX3 | |
| SCHEMBL2596820 | 0.79 | L3MBTL1 (0.30) | L3MBTL1P2RX3 | |
| SCHEMBL2598407 | 0.74 | — | — | |
| SCHEMBL8122607 | 0.68 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL2598395 | 0.67 | TGFBR1 (0.37) | — | |
| SCHEMBL8122602 | 0.66 | KDM4C (0.38) | L3MBTL1P2RX3 | |
| SCHEMBL15465385 | 0.65 | MAPK1 (0.33) | — | |
| SCHEMBL24805854 | 0.64 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL25225104 | 0.63 | CCR4 (0.34) | — | |
| SCHEMBL10433895 | 0.63 | KMT2A (0.32) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |