Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 11/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598353 | 0.81 | L3MBTL1 (0.31) | L3MBTL1P2RX3 | |
| SCHEMBL2596877 | 0.78 | L3MBTL1 (0.39) | L3MBTL1KDM4CMETP2RX3NPC1 | |
| SCHEMBL2598454 | 0.77 | MET (0.43) | L3MBTL1KDM4CMETP2RX3NPC1 | |
| SCHEMBL2598436 | 0.72 | MEN1 (0.40) | L3MBTL1KDM4CMETP2RX3NPC1 | |
| SCHEMBL26916099 | 0.70 | L3MBTL1 (0.39) | L3MBTL1KDM4CP2RX3NPC1RAB9A | |
| SCHEMBL15007862 | 0.70 | L3MBTL1 (0.56) | L3MBTL1KDM4CMETP2RX3NPC1 | |
| SCHEMBL24103542 | 0.67 | MEN1 (0.49) | L3MBTL1KDM4CMETP2RX3NPC1 | |
| SCHEMBL22638187 | 0.66 | KDM4C (0.47) | L3MBTL1KDM4CP2RX3NPC1RAB9A | |
| SCHEMBL8122602 | 0.66 | KDM4C (0.38) | L3MBTL1KDM4CP2RX3NPC1RAB9A | |
| SCHEMBL30420567 | 0.66 | MEN1 (0.43) | L3MBTL1KDM4CMETP2RX3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146287-A1 | PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-24 | — | — | WO | disclosed |