Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.59 |
| ▸ | CASP6 | P55212 | 19/20 | 0.59 |
| ▸ | CASP8 | Q14790 | 19/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390624 | 0.89 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL22390623 | 0.89 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL22404779 | 0.85 | CASP3 (0.74) | CASP3CASP6CASP8 | |
| SCHEMBL22404667 | 0.81 | KLK7 (0.47) | CASP3CASP6CASP8 | |
| SCHEMBL22390758 | 0.79 | CASP3 (0.59) | CASP3CASP6CASP8 | |
| SCHEMBL22404650 | 0.78 | CASP3 (0.41) | CASP3CASP6CASP8 | |
| Hydrochloric Acid SCHEMBL30220159 | 0.77 | CASP3 (0.41) | CASP3CASP6CASP8 | |
| SCHEMBL22404648 | 0.77 | CASP3 (0.51) | CASP3CASP6CASP8 | |
| SCHEMBL22404745 | 0.77 | KLK7 (0.46) | CASP3CASP6CASP8 | |
| SCHEMBL17261859 | 0.76 | CASP3 (0.59) | CASP3CASP6CASP8CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250067-A1 | CASPASE INHIBITORS AND METHODS OF USE THEREOF | NOBO MEDICINE INC. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250067-A1 | CASPASE INHIBITORS AND METHODS OF USE THEREOF | CASP1, CASP3, CASP7 | CASP3 2/4885CASP6 8/4885CASP8 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.