SCHEMBL25985498

SCHEMBL25985498

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc(Oc5ccc(-c6cc(-c7cccnc7)cc(-c7cccnc7)c6)cc5)cc4)cc3)n2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 8/20 0.53
CYP11B1 P15538 7/20 0.53
CYP19A1 P11511 6/20 0.53
CYP17A1 P05093 3/20 0.53
MAPT P10636 2/20 0.51
POLB P06746 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MKNK1 Q9BUB5 2/20 0.47
MKNK2 Q9HBH9 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25985506 1.00 CYP11B2 (0.53) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL21882447 0.95 MAPT (0.55) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL23370644 0.91 CYP19A1 (0.62) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL10057497 0.91 CYP19A1 (0.62) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL25985458 0.90 CYP19A1 (0.55) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL18327513 0.89 CYP19A1 (0.61) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL18327644 0.89 CYP19A1 (0.61) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL19486738 0.89 CYP19A1 (0.61) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL18327452 0.89 CYP19A1 (0.61) CYP11B2CYP11B1CYP19A1CYP17A1MAPT
SCHEMBL18327578 0.89 CYP19A1 (0.61) CYP11B2CYP11B1CYP19A1CYP17A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730009-B2 Compound and organic light-emitting element comprising same CRY2, CRY1, NR2E3 CYP11B2 1306/4885CYP11B1 2108/4885CYP19A1 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.