Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25987459 | 0.82 | MAOA (0.41) | FPR1ALDH1A1MAPTTSHRNPSR1 | |
| SCHEMBL24450176 | 0.79 | KCNH2 (0.52) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24022482 | 0.77 | PAX8 (0.42) | FPR1FPR2 | |
| SCHEMBL25986869 | 0.72 | NPY5R (0.41) | ALDH1A1MAPTMEN1KMT2AUBE2M | |
| SCHEMBL25986896 | 0.72 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL25988749 | 0.70 | KCNH2 (0.47) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24450180 | 0.67 | KCNH2 (0.51) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24022488 | 0.67 | PAX8 (0.48) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL24449479 | 0.67 | PAX8 (0.48) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL25987190 | 0.67 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600286-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES | BROAD INST INC (US) | 2023-08-16 | — | — | EP | disclosed |