Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25986896 | 0.80 | MEN1 (0.49) | NPY5RKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25987190 | 0.76 | MEN1 (0.47) | NPY5RKMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL25987459 | 0.74 | MAOA (0.41) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25987189 | 0.72 | FPR1 (0.39) | KMT2AMEN1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL25988749 | 0.70 | KCNH2 (0.47) | NPY5RKMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL24450176 | 0.70 | KCNH2 (0.52) | NPY5RKMT2AMEN1UBE2MDCUN1D1 | |
| SCHEMBL11390950 | 0.70 | NPY5R (0.50) | NPY5RKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL25988140 | 0.70 | MAPT (0.54) | NPY5RKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24022482 | 0.68 | PAX8 (0.42) | KDM4E | |
| SCHEMBL24022601 | 0.65 | UBE2M (0.50) | NPY5RKMT2AMEN1UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600286-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES | BROAD INST INC (US) | 2023-08-16 | — | — | EP | disclosed |