Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804909 | 1.00 | ACHE (0.40) | ACHEHSD11B1PPIAMEN1KMT2A | |
| SCHEMBL1804907 | 1.00 | ACHE (0.40) | ACHEHSD11B1PPIAMEN1KMT2A | |
| SCHEMBL1804905 | 1.00 | ACHE (0.40) | ACHEHSD11B1PPIAMEN1KMT2A | |
| SCHEMBL1806180 | 0.86 | ADRA2A (0.39) | HSD11B1 | |
| SCHEMBL1802527 | 0.86 | ADRA2A (0.39) | HSD11B1KMT2A | |
| SCHEMBL1806059 | 0.86 | ADRA2A (0.39) | HSD11B1 | |
| SCHEMBL1802530 | 0.86 | ADRA2A (0.39) | HSD11B1KMT2A | |
| SCHEMBL1806058 | 0.86 | ADRA2A (0.39) | HSD11B1 | |
| SCHEMBL2598922 | 0.86 | ADRA2A (0.39) | HSD11B1 | |
| SCHEMBL1804015 | 0.86 | ADRA2A (0.39) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571353-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146089-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-11-24 | — | — | WO | disclosed |