SCHEMBL2599162

SCHEMBL2599162

OCc1nnc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8770450 0.82
SCHEMBL15240198 0.72
SCHEMBL18616970 0.70
SCHEMBL8770491 0.70
SCHEMBL744617 0.65 SMN1; SMN2 (0.42)
SCHEMBL31227464 0.64 ALDH1A1 (0.47)
SCHEMBL3796364 0.61 TERT (0.40)
SCHEMBL6365255 0.55
SCHEMBL31227322 0.50
SCHEMBL17791788 0.50 NOTUM (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
EP-4271674-B3 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
US-20250340546-A1 HSD17B13 INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2025-11-06 US disclosed
US-20250312352-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2025-10-09 US disclosed
WO-2025104699-A1 URACIL COMPOUNDS ASTRAZENECA AB (SE) 2025-05-22 WO disclosed
EP-4520393-A2 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS Gilead Sciences, Inc. (US) 2025-03-12 EP disclosed
EP-4271674-B1 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-02-12 EP disclosed
US-20250026745-A1 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF MIRUM PHARMACEUTICALS, INC. 2025-01-23 US disclosed
US-20250002475-A1 PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS EPICS THERAPEUTICS (BE) 2025-01-02 US disclosed
US-12091400-B2 Piperidine derivatives as METTL3 inhibitors EPICS THERAPEUTICS (BE) 2024-09-17 US disclosed
WO-2013049559-A1 PYRIDINE DERIVATIVES ENDO PHARMACEUTICALS INC. (US) 2013-04-04 WO disclosed
US-20130085164-A1 Imidazole Derivatives ENDO PHARMACEUTICALS INC. (US) 2013-04-04 US disclosed
WO-2013049565-A1 IMIDAZOLE DERIVATIVES AS CYP17 INHIBITORS FOR THE TREATMENT OF CANCER ENDO PHARMACEUTICALS INC. (US) 2013-04-04 WO disclosed
US-20130085148-A1 Pyridine Derivatives ENDO PHARMACEUTICALS INC. (US) 2013-04-04 US disclosed
US-20130085148-A1 Pyridine Derivatives ENDO PHARMACEUTICALS INC. (US) 2013-04-04 US disclosed
US-20130085148-A1 Pyridine Derivatives ENDO PHARMACEUTICALS INC. (US) 2013-04-04 US disclosed
US-20130085164-A1 Imidazole Derivatives ENDO PHARMACEUTICALS INC. (US) 2013-04-04 US disclosed
EP-2571882-A1 HETEROCYCLIC FLAVIVIRIDAE VIRUS INHIBITORS Gilead Sciences, Inc. (US) 2013-03-27 EP disclosed
WO-2011146817-A1 HETEROCYCLIC FLAVIVIRIDAE VIRUS INHIBITORS GILEAD SCIENCES, INC. (US) 2011-11-24 WO disclosed
WO-2011146817-A1 HETEROCYCLIC FLAVIVIRIDAE VIRUS INHIBITORS GILEAD SCIENCES, INC. (US) 2011-11-24 WO disclosed