Dimenoxadol

Dimenoxadol

SCHEMBL25993

CCOC(C(=O)OCCN(C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.68
CYP2D6 P10635 3/20 0.68
LMNA P02545 3/20 0.55
ALDH1A1 P00352 1/20 0.54
CHRM2 P08172 5/20 0.53
CHRM1 P11229 5/20 0.53
CHRM3 P20309 5/20 0.53
POLB P06746 3/20 0.52
CHRM4 P08173 3/20 0.51
CHRM5 P08912 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
NPSR1 Q6W5P4 2/20 0.49
GAA P10253 1/20 0.49
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
SCN1A P35498 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimenoxadol SCHEMBL2886211 0.99 CYP3A4 (0.70) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Dimenoxadol SCHEMBL79044 0.99 CYP3A4 (0.70) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Dimenoxadol SCHEMBL5854258 0.97 CYP3A4 (0.69) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Dimenoxadol SCHEMBL2204879 0.96 CYP3A4 (0.67) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Denaverine SCHEMBL147346 0.85 CYP3A4 (0.52) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Dimenoxadol SCHEMBL4580231 0.85 CYP3A4 (0.55) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Pargeverine SCHEMBL2111437 0.85 CYP3A4 (0.51) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Denaverine SCHEMBL9569397 0.84 CYP3A4 (0.54) CYP3A4CYP2D6LMNAALDH1A1CHRM2
Pargeverine SCHEMBL30728632 0.84 CYP3A4 (0.53) CYP3A4CYP2D6LMNAALDH1A1CHRM2
SCHEMBL27585378 0.83 CYP3A4 (0.63) CYP3A4CYP2D6LMNAALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6518 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
WO-1999013799-A1 SYNERGISTIC ANALGESIC COMBINATION OF OPIOID ANALGESIC AND CYCLOOXYGENASE-2 INHIBITOR EURO-CELTIQUE, S.A. (LU) 1999-03-25 WO claimed
US-5866164-A Composition and dosage form comprising opioid antagonist ALZA CORPORATION (US) 1999-02-02 US claimed
EP-0785775-A4 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO CELTIQUE SA (LU) 1998-08-19 EP claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed