Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 12/20 | 1.00 |
| ▸ | S100A4 | P26447 | 6/20 | 1.00 |
| ▸ | CDC25A | P30304 | 8/20 | 0.71 |
| ▸ | MAP2K7 | O14733 | 7/20 | 0.71 |
| ▸ | PHGDH | O43175 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31745328 | 0.89 | CDC25B (1.00) | CDC25BS100A4CDC25AMAP2K7PHGDH | |
| SCHEMBL29527717 | 0.83 | CDC25B (1.00) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL7081685 | 0.83 | CDC25B (1.00) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL10912725 | 0.82 | CDC25B (0.69) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL10913493 | 0.80 | CDC25B (0.66) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL2599346 | 0.78 | CDC25B (1.00) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL3272454 | 0.77 | CDC25B (0.62) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL2599207 | 0.77 | S100A4 (1.00) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL2599202 | 0.77 | CDC25B (1.00) | CDC25BS100A4CDC25AMAP2K7PKM | |
| SCHEMBL17249980 | 0.75 | CDC25B (0.73) | CDC25BS100A4CDC25AMAP2K7PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | claimed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | claimed |
| US-4628062-A | 1,4-naphthoquinone derivatives having anti-inflammatory action | TROPONWERKE GMBH & CO., KG (DE) | 1986-12-09 | — | — | US | claimed |
| US-11878960-B1 | Antioxidant therapeutic potential of N,N′-diphenyl-1,4-phenylenediamine and a novel selenide on minimizing breast cancer hazards | King Faisal University (SA) | 2024-01-23 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2011146101-A1 | CHEMICAL AGENTS FOR THE PREVENTION OR INHIBITION OF TUMOR METASTASIS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090355-A1 | CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS | S100A4, S100A6, S100A10 | CDC25B 211/4885S100A4 1/4885CDC25A 248/4885 |
| US-11878960-B1 | Antioxidant therapeutic potential of N,N′-diphenyl-1,4-phenylenediamine and a novel selenide on minimizing breast cancer hazards | GPX1, GPX4, BRCA1 | CDC25B 2596/4885S100A4 783/4885CDC25A 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.