SCHEMBL2599460

SCHEMBL2599460

O=C1OCC(O)=C1c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.64
PTGS1 P23219 1/20 0.53
PTGS2 P35354 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2644702 0.82 PTGS1 (0.62) PTGS1PTGS2
SCHEMBL19335657 0.80 KMT2A (0.50) KMT2APTGS1PTGS2
SCHEMBL5071823 0.78 KMT2A (1.00) KMT2APTGS1PTGS2
SCHEMBL13483246 0.78 PRF1 (0.45)
SCHEMBL13943052 0.78 GSK3B (0.42) KMT2APTGS1PTGS2
SCHEMBL2646659 0.78 PTGS1 (0.56) PTGS1PTGS2
SCHEMBL9619055 0.78 LMNA (0.53) PTGS1PTGS2
SCHEMBL8343072 0.77 KMT2A (0.47) KMT2APTGS1PTGS2
SCHEMBL5545944 0.77 KMT2A (0.79) KMT2APTGS1PTGS2
SCHEMBL5549767 0.77 KMT2A (0.79) KMT2APTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10092881-B2 Permanent hydrophilic porous coatings and methods of making them BHA ALTAIR, LLC (US) 2018-10-09 US claimed
US-20090191399-A1 PERMANENT HYDROPHILIC POROUS COATINGS ONTO A SUBSTRATE AND POROUS MEMBRANES THEREOF GENERAL ELECTRIC COMPANY (US) 2009-07-30 US claimed
US-20090191398-A1 MEMBRANES COMPRISING HYDROPHILIC COATINGS GENERAL ELECTRIC COMPANY (US) 2009-07-30 US claimed
EP-4680252-A1 SYSTEM AND METHOD FOR FLUID CAPTURE GE Vernova Infrastructure Technology LLC (US) 2026-01-21 EP disclosed
EP-4680375-A1 SYSTEM AND METHOD FOR FLUID CAPTURE GE Vernova Technology GmbH (CH) 2026-01-21 EP disclosed
EP-4587158-A2 SYSTEM AND METHOD FOR FLUID CAPTURE USING A CROSS-LINKED BINDER General Electric Company (US) 2025-07-23 EP disclosed
CN-120091854-A System and method for capturing fluids using a cross-linked binder 通用电气技术有限公司 2025-06-03 CN disclosed
WO-2025071568-A1 SYSTEM AND METHOD FOR FLUID CAPTURE USING A SILICON-CONTAINING CROSS-LINKED BINDER GE INFRASTRUCTURE TECHNOLOGY LLC (US) 2025-04-03 WO disclosed
WO-2025038070-A2 SYSTEM AND METHOD FOR FLUID CAPTURE USING A CROSS-LINKED BINDER GENERAL ELECTRIC COMPANY (US) 2025-02-20 WO disclosed
WO-2024232943-A1 SYSTEM AND METHOD FOR FLUID CAPTURE GE INFRASTRUCTURE TECHNOLOGY LLC (US) 2024-11-14 WO disclosed
WO-2024232944-A1 SYSTEM AND METHOD FOR FLUID CAPTURE GE INFRASTRUCTURE TECHNOLOGY LLC (US) 2024-11-14 WO disclosed
US-6355638-B1 COGNITION ACTIVATORS MERCK SHARP & DOHME LTD. (GB) 2002-03-12 US disclosed
EP-1121361-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS Merck Sharp & Dohme Limited (GB) 2001-08-08 EP disclosed
WO-2001038331-A2 PYRAZOLO[1,5-D][1,2,4]TRIAZINES FOR ENHANCING COGNITION MERCK SHARP & DOHME LIMITED (GB) 2001-05-31 WO disclosed
WO-2000023449-A1 PYRAZOLO-TRIAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS MERCK SHARP & DOHME LIMITED (GB) 2000-04-27 WO disclosed
US-5708169-A BACTERICIDES FOR TREATMENT OF GRAM POSITIVE INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
EP-0623606-B1 Peptidic ketones as interleukin-1beta-converting enzyme inhibitors SANOFI SA (FR) 1998-01-07 EP disclosed
US-5585486-A Peptidic ketones as interleukin-1β-converting enzyme inhibitors STERLING WINTHROP INC. (US) 1996-12-17 US disclosed
US-5462939-A Peptidic ketones as interleukin-1β-converting enzyme inhibitors STERLING WINTHROP INC. (US) 1995-10-31 US disclosed
EP-0623606-A2 Peptidic ketones as interleukin-1beta-converting enzyme inhibitors STERLING WINTHROP INC. (US) 1994-11-09 EP disclosed